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The Vanguard Group Files Disclosure on Mural Oncology plc

The Vanguard Group, Inc. has publicly disclosed its position in Mural Oncology plc pursuant to Rule 8.3 of the Irish Takeover Panel Act, 1997. This disclosure pertains to interests in securities representing 1% or more in the company. As of November 12, 2025, Vanguard holds a 1.67% interest, equivalent to 288,731 ordinary shares at $0.01 each.

Recently, a purchase of 16 shares at a price of 2.08 USD per share was noted. There are no cash-settled or stock-settled derivatives or related agreements. Additionally, no collateral arrangements or commitments are linked to this disclosure.

There is no supplementary Form 8 attached to this disclosure. Details on voting rights or further acquisitions linked to derivatives were also absent.

R. H.

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